Paramyxovirus
Ferlavirus, fam. Paramyxoviridae
The best known viral cause of epidemic respiratory disease in snakes, historically devastating in viperid collections. [1][2][3]
- Method
- PCR
- Sample material
- Oral swab
- Catalogue code
- PMV
The pathogen
Enveloped, single-stranded negative-sense RNA virus of the genus Ferlavirus. Fragile outside the host but readily carried on hands, hooks and shared equipment.
Transmission
Direct contact and aerosol between animals, and indirectly by keepers, tools and enclosure furniture. Clinically healthy carriers can shed for long periods, which is why screening asymptomatic animals matters.
Pathology
- Proliferative interstitial pneumonia with hyperplasia of the faveolar epithelium
- Pulmonary oedema and exudate in the lung and air sac
- Occasional non-suppurative encephalitis and pancreatitis
- Frequent secondary bacterial infection of the damaged airway
Clinical signs
- Open-mouth breathing, nasal and oral discharge, audible respiration
- Head tremor, loss of righting reflex, star-gazing in neurological cases
- Regurgitation, weight loss, sudden death without warning signs
Prevention
- Quarantine every new arrival for at least 3 months and test before introduction
- Test breeding stock annually and before sale or exchange
- Strict one-way workflow: healthy animals first, quarantine last
- Dedicated tools per enclosure; disinfect with a virucidal agent effective on enveloped viruses
Treatment options
No specific antiviral therapy exists. Care is supportive — correct temperature gradient, fluids, nutritional support and antibiotics against secondary bacterial pneumonia. Infected animals should remain permanently separated from the collection.
References
- [1]Hyndman TH, Shilton CM, Marschang RE (2013). Paramyxoviruses in reptiles: a review. Veterinary microbiology 165:200-13. DOI: 10.1016/j.vetmic.2013.04.002 · PMID: 23664183
- [2]Kolesnik E, Hyndman TH, Müller E, Pees M, Marschang RE (2019). Comparison of three different PCR protocols for the detection of ferlaviruses. BMC veterinary research 15:281. DOI: 10.1186/s12917-019-2028-0 · PMID: 31387580
- [3]Marschang RE, Salzmann E, Pees M (2021). Diagnostics of Infectious Respiratory Pathogens in Reptiles. The veterinary clinics of North America. Exotic animal practice 24:369-395. DOI: 10.1016/j.cvex.2021.01.007 · PMID: 33892892
Order a kit
Prepared for your animal and typically delivered within 7 days
Send the samples
Take the sample and send it directly to the laboratory
Receive the test result
Typically within 7 days after the laboratory receives the sample
This profile is reference information for keepers and breeders. It is not a diagnosis and does not replace veterinary advice. Medicines mentioned are prescription-only and must be used under veterinary supervision.
