VETERINARIAN-LED · REPTILE HEALTH REGISTRY · EUROPE
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§ — PATHOGEN PROFILE · PMV

Paramyxovirus

Ferlavirus, fam. Paramyxoviridae

The best known viral cause of epidemic respiratory disease in snakes, historically devastating in viperid collections. [1][2][3]

Method
PCR
Sample material
Oral swab
Catalogue code
PMV

The pathogen

Enveloped, single-stranded negative-sense RNA virus of the genus Ferlavirus. Fragile outside the host but readily carried on hands, hooks and shared equipment.

Transmission

Direct contact and aerosol between animals, and indirectly by keepers, tools and enclosure furniture. Clinically healthy carriers can shed for long periods, which is why screening asymptomatic animals matters.

Pathology

  • Proliferative interstitial pneumonia with hyperplasia of the faveolar epithelium
  • Pulmonary oedema and exudate in the lung and air sac
  • Occasional non-suppurative encephalitis and pancreatitis
  • Frequent secondary bacterial infection of the damaged airway

Clinical signs

  • Open-mouth breathing, nasal and oral discharge, audible respiration
  • Head tremor, loss of righting reflex, star-gazing in neurological cases
  • Regurgitation, weight loss, sudden death without warning signs

Prevention

  • Quarantine every new arrival for at least 3 months and test before introduction
  • Test breeding stock annually and before sale or exchange
  • Strict one-way workflow: healthy animals first, quarantine last
  • Dedicated tools per enclosure; disinfect with a virucidal agent effective on enveloped viruses

Treatment options

No specific antiviral therapy exists. Care is supportive — correct temperature gradient, fluids, nutritional support and antibiotics against secondary bacterial pneumonia. Infected animals should remain permanently separated from the collection.

References

  1. [1]Hyndman TH, Shilton CM, Marschang RE (2013). Paramyxoviruses in reptiles: a review. Veterinary microbiology 165:200-13. DOI: 10.1016/j.vetmic.2013.04.002 · PMID: 23664183
  2. [2]Kolesnik E, Hyndman TH, Müller E, Pees M, Marschang RE (2019). Comparison of three different PCR protocols for the detection of ferlaviruses. BMC veterinary research 15:281. DOI: 10.1186/s12917-019-2028-0 · PMID: 31387580
  3. [3]Marschang RE, Salzmann E, Pees M (2021). Diagnostics of Infectious Respiratory Pathogens in Reptiles. The veterinary clinics of North America. Exotic animal practice 24:369-395. DOI: 10.1016/j.cvex.2021.01.007 · PMID: 33892892
  1. Order a kit

    Prepared for your animal and typically delivered within 7 days

  2. Send the samples

    Take the sample and send it directly to the laboratory

  3. Receive the test result

    Typically within 7 days after the laboratory receives the sample

This profile is reference information for keepers and breeders. It is not a diagnosis and does not replace veterinary advice. Medicines mentioned are prescription-only and must be used under veterinary supervision.